Is Covid 19 autoimmune high risk?

Inflammatory phase of COVID-19 – Dr. Moisés Labrador

In addition, having an autoimmune disease is a factor associated with a higher risk of having a worse evolution once admitted to the hospital. According to the RIER study, this is linked to more serious complications than patients without these diseases.

In Pablos’ opinion, the possible role of previous therapies used in chronic arthritis or autoimmune diseases is not fully established. Among the therapies that may increase the risk are corticosteroids, although their use cannot generally be discontinued.

In addition, recommendations are collected on patients in outpatient consultations both at the patient’s admission. In cases of hospitalization, it is advisable to perform all the complementary explorations that are possible on an outpatient basis, thus avoiding prolonged admission of the patient; as well as favoring early discharge and home hospitalization.

With respect to diagnostic/therapeutic procedures and techniques, an individualized evaluation should be made to extend the interval for analytical studies in stable patients with no previous analytical alterations. Likewise, the prescription of complementary examinations that are not essential should be avoided.

Primary immune thrombocytopenia in the COVID-19 era.

In this case, actions are taken to make the treatments required. Autoimmune diseases have become a major health challenge, as they are diseases that destabilize the body and cause the immune system to attack the healthy cells of our patients.

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In addition, immunosuppressive treatment has also been associated with an increased risk of infection by making it more difficult for immune system cells to clear the virus. One might think, therefore, that in the current situation it would be best to abandon immunosuppressive treatment. But, in fact, studies show the opposite: the risk of the autoimmune disease itself flaring up would be more serious than the risk of catching an infection. Therefore, one of the clearest recommendations is that patients should not abandon their basic treatment.

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Therefore, nowadays, the recommendations that can be made to people with an autoimmune disease are to maintain the general measures of social distancing, the use of masks and frequent hand washing. In addition, they should not abandon their basic immunosuppressive treatment and, in case of suspicion of coronavirus infection, they should contact their physician, who will give them the most appropriate instructions in each case.

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In addition to age, certain underlying concomitant conditions and diseases have been described as increasing the risk of disease and its progression. These include medical conditions that lead to a state of immune deficit, or alteration of the local defenses of the target organ, such as chronic renal, hepatic, respiratory and cardiovascular disease; HIV-infected patients; patients awaiting solid organ transplantation and solid organ and/or hematopoietic progenitor transplant recipients; patients undergoing chemotherapy for solid tumor or hematopoietic stem cell transplantation; patients undergoing chemotherapy for solid tumor or hematopoietic malignancy; patients with autoimmune disease and treated with corticosteroids, immunosuppressants or biologics; diabetic patients; patients with cerebrospinal fluid fistulas, cochlear implants as well as patients with anatomical or functional asplenia.

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